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to study the molecular and cellular mechanisms involved in brain activity. The Institute develops innovative methods in imaging, chemistry, physiology and computer science. As part of Bordeaux Neurocampus
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to study the molecular and cellular mechanisms involved in brain activity. The Institute develops innovative methods in imaging, chemistry, physiology and computer science. As part of Bordeaux Neurocampus
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to study the molecular and cellular mechanisms involved in brain activity. The Institute develops innovative methods in imaging, chemistry, physiology and computer science. As part of Bordeaux Neurocampus
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combination of high-end microscopy combined with fluorescent biosensor imaging, optogenetics and genetically-encoded molecular tools enabling subcellular manipulation in vitro and in vivo. She/He will also work
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for manufacturing chiral metal nanoclusters of different sizes, metal compositions and degrees of chirality (intrinsic and induced). The main objective is to use the nanoclusters designed both as multiphoton imaging
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environment, with access to state-of-the art brain imaging facilities (two research-dedicated MRI scanners / 1.5 and 3T, hybrid PET-3T MRI, MEG-EEG). The vibrant research community at CRNL and other nearby
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equipment, particularly in imaging and electron microscopy, image analysis, and bioinformatics. The team is composed of five people. The thesis will be carried out as part of a collaborative ANR project
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influence helps detect labeling errors or prioritize unlabeled images, optimizing the learning algorithm and service quality. The doctoral student will carry out their work at IMAG (UMR of Mathematics) and
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fibrosis; transcriptomic and imaging approaches (RNA-seq), high-content imaging (ImageStream), and metabolic profiling (Seahorse); recombinant protein engineering; structural biology techniques: X-ray
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), Biochemistry (production and purification of protein complexes), Structural biology (cryo-electron microscopy and image analysis). The final goal is to build a mechanistic model of substrate recruitment by