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of chemobiology, numerous probes have been designed to monitor metabolic processes in biological systems in real time. The vast majority of these are off-on probes detected by imaging, which, when used in vitro
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institute hosts an interdisciplinary neuroscience community with access to several brain imaging facilities, such as one research-dedicated 3T scanner, MEG/EEG, TEP, TMS/tDCS and other useful resources (https
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fibrosis; transcriptomic and imaging approaches (RNA-seq), high-content imaging (ImageStream), and metabolic profiling (Seahorse); recombinant protein engineering; structural biology techniques: X-ray
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using imaging and behavior platforms at SPPIN. This project will allow the control of MeCP2 expression in order to optimize the efficacy of RTT gene therapy, while establishing a modular framework for
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), Biochemistry (production and purification of protein complexes), Structural biology (cryo-electron microscopy and image analysis). The final goal is to build a mechanistic model of substrate recruitment by
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, paleopathologies, etc.), supervise/coordinate additional analyses (medical imaging, chemical, isotopic and DNA analyses, etc.) in collaboration with partner laboratories; - Contribute to the project's scientific
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techniques) - Fluorescence microscopy, data processing applied to image analysis - Basic mathematical skills (proportionality rules) + statistical analysis - Knowledge of molecular mechanisms of bacterial
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to develop an innovative individualized neurofeedback software suite for ADHD remediation, combining fMRI and EEG. The postdoctoral researcher will work closely with imaging engineers (CERMEP), ADHD clinical
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Information Eligibility criteria The candidate must: - Hold a PhD in microbiology or cell biology - Have significant experience in fluorescence microscopy: time-lapse, dynamic imaging, multi-channel, etc
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for therapeutic applications in hypoxic tumors, with the goal of improving the efficacy of radiotherapy. This interdisciplinary project is a collaboration between ISTCT/CNRS, expertise in imaging, radiotherapy, and