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methods of neural-microglia interactions, complementing already established multi-omics approaches: non-destructive fluorescence lifetime imaging microscopy (FLIM), mass spectrometry imaging and Raman
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evolutionarily recent genes may buffer or exacerbate these effects. About the Labs The Bonin Lab investigates cortical circuit function in sensory systems using in vivo imaging and computational modeling
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evolutionarily recent genes may buffer or exacerbate these effects. About the Labs The Bonin Lab investigates cortical circuit function in sensory systems using in vivo imaging and computational modeling
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(bio-)chemistry, physics, and engineering expertise to study molecules and cells, taking advantage of optical and single-molecule imaging, molecular probes, molecular biology, and 'large' data analysis
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genetics of disease models, human pluripotent stem cells derived neurons, high content imaging, electrophysiology, single cell RNA sequencing, bioinformatics, and spatial transcriptomics technologies. We
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protein, cause a broad range of neurogenetic disorders. You will use iPSC-derived neurons to study cytoskeletal abnormalities through cutting-edge microscopy and image analysis, functional assays, and
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imaging of mouse and human urothelium, X-ray videocystometry in awake mice, and optogenetic modulation of urothelial cells. The candidate will design and conduct experiments exploring mechanosensitive ion
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investigating sensory signaling in the bladder wall and its role in lower urinary tract disorders (LUTd). The project involves advanced techniques such as ex vivo calcium imaging of mouse and human urothelium, X
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the developmental programs that shape inhibitory circuits in the brain. We use various interdisciplinary techniques such as mouse genetics, high content imaging, single cell RNA sequencing, and spatial
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live-cell imaging, we can now explore hormone regulation at unprecedented single-cell resolution. Using these tools, we have observed dynamic fluctuations in brassinosteroid signalling throughout