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disease models. The project offers training at the crossroads of protein engineering, structural biology, and cancer biology, and will provide the candidate with a strong interdisciplinary skill set that is
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, The Netherlands) in the lab of Dorota Durek to test an engineered protease inhibitor in an in vitro model of skin scarring. More information on the scientific project is available here: Titre: Elucidation
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spanning molecular genetics, genomics, cell biology to biophysics, mathematics and computational modeling. The laboratory is housed at ENS de Lyon, a top-ranking French university, situated in the vibrant
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intelligent decisions. In particular, when low latency is critical, these models are deployed directly on devices at the edge, close to the equipment itself — a necessary condition for smarter, faster
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of isolated clones using biochemical, biophysical and imaging methods. Engineering of protein tools using chemical or genetic methods for use in a cellular environment. Validation of tools in cellular models
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model that explains lattice distortions and branching mechanisms. (4) Analyze experimental data using advanced computational tools and present results in research meetings and scientific publications
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interpersonal skills and be rigorous and organised in his/her work. Experience in molecular/cellular biology and murine models is required. Experience in omic approaches,single cell RNA-seq technologies and
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chemistry, materials science or equivalent having carried out research in an experimental field related to the thesis. Core competencies: crystal growth thermodynamic modeling chemical and physical
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experimental development, physicochemistry, and multiscale modeling for the implementation of innovative extraction technologies aimed at processing complex, polymetallic, and unconventional resources while
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), Biochemistry (production and purification of protein complexes), Structural biology (cryo-electron microscopy and image analysis). The final goal is to build a mechanistic model of substrate recruitment by