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that regulate R-loops in human cells and discovered a role for the tumor suppressor DDX41 in R-loop resolution. PhD Project: Mechanisms opposing R-loop-associated DNA double strand breaks The PhD project will be
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groups in Mainz (Schweiger lab) and Basel (Keller Valsecchi lab) to investigate the molecular mechanisms controlling gene reactivation during development. Using human induced stem cell models with
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production, antibody binding assays, germ-free and gnotobiotic mouse models and human samples, bacterial transcriptomics, and single cell host transcriptomic analysis to obtain a detailed mechanistic
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scientific projects and labs. The projects address the three “One Health” aspects: 1) human roundworm infections (close cooperation and fieldwork in Kenya / Africa), 2) roundworm infections in farm animals
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the human brain injury environment and strategies for neuronal replacement through glia-to-neuron reprogramming. Methods include proteomics, decellularization of human brain tissue, iPSC-derived neurons/glia
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, HHU Düsseldorf). Prof. Amunts is a leading expert in brain mapping and the development of human brain atlases at microscopic scale. Her group pioneered the Julich-Brain and BigBrain projects using deep
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the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz - WissZeitVG). The position aims at obtaining further academic qualification (usually PhD). Professional assignment: Chair of Knowledge
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. This unique program offers an intensive interdisciplinary approach, with a special focus on sustainable metallurgy – a field that has shaped human civilization by providing crucial materials for mobility
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the face of DNA damage. On the other hand, we investigate the diverse signalling functions of the posttranslational protein modifiers, ubiquitin and SUMO. Most of our ongoing projects are therefore situated
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. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz - WissZeitVG). The positions offer the chance to obtain further academic qualification (usually