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. This is because experimental techniques to solve structures of protein complexes favor more stable interactions with larger interfaces and because we lack efficient algorithms to compute similarity between
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, I identified multiple novel direct interactors of UAP56, which appear to either stall or shortcut mRNA export. Using a combination of biochemical reconstitution, genetic approaches in the powerful
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memory of paternal DNA damage The transgenerational effect of DNA damage has been previously studied through epidemiological and genetic approaches, but these have yielded contradictory results. Recently
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independent mode of genetic reprogramming shaping cancer’s cell fate. We thus foresee that the epitranscriptome will prove to be a fundamental layer of gene regulation amenable to the clinics as a valuable tool
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, or conditional deletion of defined dendritic cell subsets, providing powerful genetic tools for dissecting cell-specific roles in vivo. Using and optimizing these tools to study Type 3 Dendritic cells in mouse