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biochemical reconstitution, electron cryomicroscopy (cryo-EM), advanced bacterial genetics, and phage biology to explore how cells and viruses control the three-dimensional structure of DNA. We investigate how
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structural), ECG, and genetics, to model disease trajectories and improve risk prediction in cardiomyopathies. The successful applicant will work closely with the PI to deliver research projects, supervise
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renewable award. You will lead a programme of research in the molecular mechanisms of cardiovascular disease, that may include a range of approaches including targeted genetic murine models, primary cell
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purification, and recombinant DNA techniques. Experience of isolating proteins at native expression levels or from membranes, expertise in bacterial genetics, and expertise in quantitative fluorescence
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vascular biology) alongside experience in cell biology and cell signalling in isolated primary cells. You must also have experience in phenotyping of genetically modified experimental models
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: analytical and forensic science; asthma and allergy; biophysics and cell biology; cancer; cardiovascular; nutrition and diabetes; genetics; infection and immunology; imaging and biomedical engineering