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), based at the Centre for Human Genetics, University of Oxford. The post aims to assist with the preparation and molecular characterisation of tumours using multi-omic analysis focusing principally
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the lab. This work will explore the molecular mechanisms of DNA damage responses and mutagenesis, and how sensitivity and resistance arise in different cancer cells and genetic backgrounds in response
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biology, biochemistry, and cell biology techniques (e.g. molecular cloning, protein and RNA extraction, PCR, gel electrophoresis, western blotting, mammalian cell culture, genetic manipulation of cells
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and Immigration website . Full-Time, Fixed-Term (36 months) We are looking for a highly motivated early career researcher with a PhD (or near completion) in psychology, life sciences, genetics
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have collated and curated the world’s largest publicly available dataset of M. tuberculosis samples with both genetic and drug susceptibility testing data. This data has many potential uses within
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based on the understanding that early experience shapes the way our brain is constructed. While the “ground plan” of the brain is genetically determined, it is also influenced by environmental experience
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approaches including targeted genetic murine models, primary cell culture and analysis, multi-omics and bioinformatics. The biological focus will be on vascular biology, immune cell function and metabolism
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be expected to lead the project with the supervisor and take responsibility for practical work including: molecular biology, C. elegans maintenance, genetics, and transgenics, live fluorescence
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in cancer and infection, their involvement in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how
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in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling