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with core data analysis and professional skills that are necessary for bioscience research and related non-academic careers. https://www.yorkshirebiosciencedtp.ac.uk Project Description: Join an exciting
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of designing, performing and analysing in vitro GPCR cell signalling assays to a high standard Experience of designing and optimising molecular biosensors e.g. for BRET, FRET Knowledge of current therapeutic
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covering technical capabilities for live-cell imaging, spectral imaging, FRET, FLIM, airyscan imaging, bioimage processing, analysis and data visualization. More information about instrumentation at ALMU
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the Molecular Crowding of Ligand-Induced Riboswitch Folding: Kinetic/Thermodynamic Insights from Single Molecule FRET Spectroscopy”, J. Phys. Chem. 126, 6419–6427 (2022) https://doi-org.colorado.idm.oclc.org
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-molecule FRET. The interdisciplinary approach of this project provides scope for students to shape the project, which is enhanced by specialist networks in the University of Sheffield, including the Nucleic
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receptors. These ligands will be coupled to elastic peptides labeled with fluorophores, then grafted onto fluorescent nanoparticles to enable tension measurement via ratiometric FRET. The functional
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purification of fluorescently labelled proteins and chromatin Research on protein-chromatin interactions using single-molecule FRET Design of mutations in transcription factors Where to apply Website https
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is also known for the development of the Nanoimager microscope and the founding of Oxford Nanoimaging (https://oni.bio/ ). The group recently moved in the new Kavli Institute for Nanoscience Discovery
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, PNAS 2020; Mazumder, eLife 2021; El Sayyed et al Mol Cell 2024). The group is also known for the development of the Nanoimager microscope and the founding of Oxford Nanoimaging ( https://oni.bio
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at the University of Graz, Austria. About the Position: This role focuses on developing advanced single-molecule fluorescence and microfluidic approaches (confocal, TIRF, single-molecule FRET) for biophysics