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The LIT - Leibniz Institute for Immunotherapy (foundation under civil law) (https://lit.eu/ ) - is a biomedical research center focusing on translational immunology in the fields of cancer
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cooperation partners in their research projects with state-of-the-art light and electron microscopes (https://www.leibniz-fmp.de/cellular-imaging ). We work with proteins, cell cultures, and model organisms
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Postdoctoral Position and Postdoctoral Fellowship (2yrs) in Intracellular Host-Pathogen Interactions
experience in molecular genetic approaches, fluorescence microscopy, mammalian cell culture, and intracellular infection models. Candidates should be passionate about scientific discovery, motivated to tackle
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of Prof. Jennifer McManus, examining protein phase transitions associated with biomolecular condensation in-vitro using a range of scattering and fluorescence microscopy techniques. The overall aim is to
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://doi.org/10.1126/science.1253920 [2] An RNA origami robot that traps and releases a fluorescent aptamer. Science Advances (2024). https://doi.org/10.1126/sciadv.adk1250 Your qualifications: Required
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offices. The department maintains an impressive suite of instrumentation including a Bruker 400 MHz NMR, Agilent LC/Q-TOF Mass Spectrometer, GC/MS, HPLCs, IR, UV/Vis, and fluorescence spectrometer
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modern faculty offices. The department maintains an impressive suite of instrumentation including a Bruker 400 MHz NMR, Agilent LC/Q-TOF Mass Spectrometer, GC/MS, HPLCs, IR, UV/Vis, and fluorescence
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://doi.org/10.1126/science.1253920 [2] An RNA origami robot that traps and releases a fluorescent aptamer. Science Advances (2024). https://doi.org/10.1126/sciadv.adk1250 Your qualifications: Required
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. BioRxiv 2024; doi: https://doi.org/10.1101/2024.04.15.589474 ). In this PhD project, we will validate these molecules and interrogate their mechanism of action using confocal microscopy, protein chemistry
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that the toxin induces DNA damage responses in cultured cells that activates a senescence tumour suppressor mechanism (https://doi.org/10.1038/s41467-019-12064-1). Cells undergoing toxin-induced senescence undergo