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which unique properties of motor and sensory neurons make them more vulnerable to neurodegeneration. You will use viral gene transfer, fluorescence-activated cell sorting, next-generation sequencing
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from organic sugar synthesis to their visualization by fluorescence microscopy at various levels of resolution, including their validation in different cellular models. You will have to regularly present
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including single-cell genomics by next-generation sequencing, in situ single-cell analyses of DNA and RNA by Fluorescent in situ Hybridization (FISH), and CRISPR gene editing to induce genomic instability and
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) and immunoassays (ELISA); Bacterial culture and transformation; molecular cloning; Experience with immunocytochemical techniques and fluorescence microscopy; Programming in Python; Independence and
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organoids Experience in gene therapy research Experience in fluorescence and confocal microscopy Processing and analysis using image‑analysis software Experience in research within cellular reprogramming More
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ideal for candidates seeking hands-on experience in translational neuroscience and laboratory-based preclinical research. 📄 Full Call & Requirements: https://drive.google.com/file/d
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for mitochondrial mRNA levels and degradation using a fluorescent microscopy-based approach. The proteins identified in this screening will be further characterized through various molecular, biochemical, and
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qualifications An M.D., Ph.D. or M.D./Ph.D. is required Preferred qualifications Candidates with a background in vascular biology, cell and developmental biology, mouse genetics, fluorescence microscopy and/or
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fundamental laboratory science with clinical research as part of the Mental Health, Dementia and Neurodegeneration Research Theme https://www.ncl.ac.uk/medical-sciences/research/research-themes/mental-health
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sequencing analysis Clone DNA and propagate in bacteria Culture and transfect mammalian cells Perform Northern and Western blot analyses Perform fluorescence microscopy and luciferase assays, including data