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cryo-EM, cryo-ET, FIB milling, and biochemical methods to understand mechanisms of dynein-2 transport, building on recent advances in the group (NSMB 2017 PMID 28394326; NSMB 2019 PMID: 31451806; Cell
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of novel strategies for neuronal analysis in health and disease and optimizing novel methods. The project is funded by My Name’5 Doddie Foundation, as part of their Catalyst Awards. Using iPSC-neurons, our
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plasmas, including via methods based upon Molecular Dynamics and Particle-in-Cell techniques as well as experiments. We also envision that the ideal candidates will provide support to experimentalists and
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of recombinant proteins as well as biochemical and biophysical characterisation methods are essential. You will possess sufficient knowledge and experience in mammalian cell culture and associated cell-based
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; • professional experience with force spectroscopy methods (e.g. optical tweezers, magnetic tweezers, or atomic force microscopy) is a plus; • interesting in developing a biochemistry skillset to enable