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PhD Studentship: Nanopore Technology for Rapid and Accurate Measurement of Antibiotic Concentrations
for small-molecule sensing. By engineering nanopores with molecular recognition elements such as DNA aptamers, this project will enable multiplexed, real-time detection of diverse antibiotics, supporting both
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learning and machine learning for biological data Sequence and structure analysis of large-scale datasets Functional annotation and evolutionary analysis Collaborative research with experimental virology
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. These mobile genetic elements autonomously transfer between bacteria, disseminating resistance genes across microbial populations. Recent advances have demonstrated the potential of “counter-plasmids” that can
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treatment outcomes in vulnerable populations. Training and Student Development: The student will receive interdisciplinary training in: Peptide synthesis and structural analysis Advanced mass spectrometry
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Develop an active learning-driven platform for compound selection and optimisation Integrate robotic sample preparation, automated data acquisition, and computational analysis Advance five existing
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tracking. • Quantitative image analysis to assess spatial dynamics of gene transfer. Impact and Outlook This project will: Establish proof of concept for surface-based AMR control. • Inform the design of
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Student Development The successful applicant will gain expertise in: Biophysical imaging (AFM, microscopy) Microbiology and molecular biology RNA sequencing and data analysis Interdisciplinary collaboration
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mining and assembly to recover host-phage associations. Phylogenetic analysis of recovered co-evolutionary relationships. Gene annotation and comparative genomics to identify candidate antimicrobial
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single-component organic solar cell materials and how a temperature gradient is converted to electricity in organic thermoelectrics. An important aim of the simulations us to derive generally applicable
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culture and in vitro models of mucosal immunity Data analysis using Python and digital image processing These skills are highly transferable to careers in biomedical research, pharmaceutical development