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PhD studentship: Defining the role of the pioneer factor FOXA1 in hormone-dependent cancer Supervisor: Professor Jason Carroll Course start date: 1st October 2026 Project details For further
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transcriptomics and histone mark profiling as well as by live imaging approaches. As part of this project, you will have the opportunity to gain computational data analysis skills. This studentship comes with
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of cancer, namely adenocarcinoma, which was driven by a transcriptional pathway that involves Androgen Receptor (AR) and a pioneer factor called FOXA1 that helps tether AR to the chromatin. Recent new
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: Advanced molecular and protein analysis Mass spectrometry-based imaging Multi-omics technologies Preclinical cardiometabolic animal models They will also gain professional development in data stewardship
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technologies, bulk and single-cell RNA-sequencing, flow cytometry, multiplex immunofluorescence, and standard molecular biology and biochemistry techniques. A computational component may also be available
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hands-on and applied, with modules such as: Applied Nanoscience, an introductory module covering core topics in Nanoscience research, experimental skills and data analysis through lab practicals; Systems
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metabolomic and lipidomic analysis. References/further reading Stockis J, Yip T, Raghunathan S, Garcia C, Lee S, Simpson C, Pinaud S, Schuijs MJ, Araos Henríquez J, Png S, Raddi G, Bricard O, So TY, Mack S
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. Initial analysis suggests recurrent selection of divergent types in multiple locations. The aim of this role is to complete this analysis and prepare a manuscript for submission for publication
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-based reviews, data collection and analysis, written outputs, and the dissemination of research findings to different audiences, including through investor briefings and academic publications. We
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codes for analysis; coordinate with the PI and Lab Manager; participate in regular group meetings and other group activities. Fixed term: The position is available with a flexible starting date. The funds