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lines; generation of samples for proteomics analysis Data integration and analysis, including transcriptomic, proteomic and library screen data Target validation by CRISPR-Cas9 knockouts in primary AMLs
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degree in (analytical) chemistry, biochemistry, or a related discipline Hands-on experience in mass spectrometry-based proteomics (e.g. DDA, DIA, PRM) Experience with proteomic data analysis Computer
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functional cell assays Interest in translational leukemia research and innovative imaging and omics technologies Bioinformatics experience, especially in R Ideally initial experience with image analysis, laser
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of primary cardiomyocytes and analysis of contractility and calcium transients Establishment of in vivo disease models to test therapeutic efficacy of S100A1ct and other S100A1-derived peptides Interaction
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of experiments within the framework of the scientific project plan Develop and establish new methods in the laboratory to enable new research approaches Isolation of primary cardiomyocytes and analysis
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, data collection, and data analysis as outlined in the research plan and collaborate with others. Collaborate with biostatisticians or data analysts, if required, to interpret and analyze complex data
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analysis, cloning, cell culture, lentiviral transductions, flow cytometry, microscopy etc.), experience in NGS data analysis, CRISPR technologies, RNA interference Experience in writing scientific reports