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explants, in vivo models and patient samples of type 2 immune disease will be critical to map and characterize key events that lead to different qualities of type 2 immunity and experimentally validate
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production, antibody binding assays, germ-free and gnotobiotic mouse models and human samples, bacterial transcriptomics, and single cell host transcriptomic analysis to obtain a detailed mechanistic
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on a single cell level. This includes single-cell RNAseq datasets and analysis tools, large high-dimensional flow cytometry phenotyping panels and a collection of transgenic mouse models specifically
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groups in Mainz (Schweiger lab) and Basel (Keller Valsecchi lab) to investigate the molecular mechanisms controlling gene reactivation during development. Using human induced stem cell models with
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, providing a solid foundation for further investigation. Your tasks and responsibilities Develop and validate cellular models of acute paralogue dysfunction in developmental contexts (e.g. degrons) Map binding
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Bremen, a private, state-accredited, English-language research university. Our research group focuses on modeling dynamical processes in (bio)molecular systems using quantum and classical approaches
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approaches in the powerful model systems zebrafish and fruit fly, and structural biology (including AlphaFold predictions and cryo-EM), we will dissect the roles of these novel mRNA export regulators and
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budding yeast and human cells as models. PhD Project 1: Deciphering the ubiquitin code The ubiquitin system plays a key role in determining the function and fate of proteins in virtually every biological
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days off on 24 / 31 December family-friendly, flexible working time model VBL - pension scheme in the public sector wide range of individual training opportunities extensive health and sports programs
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days off on 24 / 31 December family-friendly, flexible working time model VBL - pension scheme in the public sector wide range of individual training opportunities extensive health and sports programs