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-dimensional single-cell analysis technologies and spatial proteogenomics to dissect interaction networks between immune cells and the tumor microenvironment. The post holder will develop experimental work flows
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growth, uncovering the MAP3K8-mediated translational programs that are involved and setting the clinical relevance of inhibiting the translation machinery for poor-prognosis lung cancer patients
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models will be used to unravel niche-driven leukemia initiation mechanisms. Ectopic humanized in vivo BM-AML organoids will be used to validate the identified therapeutic targets. The post-doctoral fellow
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