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PhD position understanding and designing nanomedicines-membranes interaction: physics based approach
the nanomedicines with high specificity to the desired target site in the body. In this PhD project, the candidate will experimentally study how to achieve high specificity by developing a quantitative understanding
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is to deliver the nanomedicines with high specificity to the desired target site in the body. In this PhD project, the candidate will experimentally study how to achieve high specificity by developing
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autoimmune conditions. The project is a shared position between the CBI-department (Leiden University) and the haematology- and experimental rheumatology departments of the Leiden University Medical Centre and
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the haematology- and experimental rheumatology departments of the Leiden University Medical Centre and candidates are trained at both research institutes. We are therefore looking for a highly motivated
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PhD candidate in Design and synthesis of pyrophosphate mimetics to study enzymes involved in natural
by ADP-ribosyltransferases of the PARP family, while ADP-ribosylhydrolases remove the ADP-ribose residue. Understanding the detailed mechanisms of such modification and demodification is vital
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that restore immune function could therefore have substantial therapeutic applications. Cellular metabolism is an important mechanism regulating immune function. This PhD project will use a combination of
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methods. They will be responsible for characterizing the mechanisms of novel bioactive compounds and the medicinal chemistry optimization of these molecules. The candidate will be trained in a variety of