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myeloproliferative neoplasms (MPNs). You will take a lead role in conducting wet lab experimentation, applying state-of-the-art single-cell multiomic approaches and functional genomic screens to patient-derived
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responses in the context of inflammatory bowel disease and other mucosal barrier disorders. A central aim will be to define the mechanisms by which metabolites such as butyrate shape antimicrobial programmes
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mechanisms by which co-inhibitory receptors, including PD-1, BTLA, TIGIT, and CD200R, regulate T cell function in autoimmune settings. Despite sharing common downstream signalling components such as SHP1 and
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executing research programmes related to different aspects of thymus biology employing informative experimental models and a broad range of analytical platforms, including single cell transcriptomic analysis
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the Department of Engineering Science. The post is funded for a 2-year fixed term. You will be actively involved in developing and running experimental facilities at the Oxford Thermofluids Institute
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. To address these questions, we combine a series of interdisciplinary approaches ranging from experimental embryology and fluorescent microscopy to mathematical modelling. The lab is highly interdisciplinary
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About the role The Lu lab is interested in the mechanism by which cancer karyotype mutates and becomes resistant to therapy, with the aim of finding new ways to treat cancer more effectively. We
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research centre within the Departments of Experimental Psychology and Psychiatry where differences between children and young people are understood and accepted, strengths are capitalised on, and mental
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records of experimental work and findings. You will take initiatives in the planning of research; conduct and plan own scientific work with appropriate supervision and present findings to colleagues within
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enhancing the clinical relevance of experimental findings and supporting the development of novel therapies. You will be responsible for planning, managing and conducting the academic research project and