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of inflammation on therapy resistance in colorectal cancer. Our lab is focused on understanding the cellular and molecular mechanisms promoting metastasis and therapy resistance in colorectal cancer. We use single
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About the Role Applications are invited for a full-time Postdoctoral Research Assistant to investigate mechanical sensing and mechanical memory in cardiac muscle cells and its involvement in
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-funded research project aims to determine how the integrin alpha-v beat-6 promotes metastasis. We have identified novel data that suggests an unexpected mechanism may be a major player in some cancers. We
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project investigating mechanosensing in Diptera. This post will focus on using detailed wing geometry models and kinematic measurements in computational fluid and structural dynamics simulations to recover
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experimental approaches to develop and validate novel in vitro and ex vivo approaches that model arterial medial calcification without using any animal products. This work will represent an exciting step forward
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, dynamic and growing discovery research group as a postdoctoral researcher. The postholder will work in Dr Knuepfer’s group, whose team explores molecular mechanisms of red blood cell invasion by malaria
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of Spiralian Asymmetric Cell Divisions”. This research position will reveal the mechanisms that drive the evolution of polar lobes during the first asymmetric cell divisions in animals with spiral cleavage. We
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, with strong expertise in experimental multi-omics techniques and computational biology alongside experience with flow cytometry and bulk/single cell bioinformatics in genomics/transcriptomics. About the
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on the molecular mechanism of DNA replication initiation in bacteria. This work is aimed at unravelling the sequence of events that lead to helicase loading during initiation and restart. This structural biology
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infrastructure enables recruitment of 200-300 severely injured patients annually as part of the ACIT study. We also have a well-established experimental modelling group with full ethical approvals in place for all