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developing genetic risk scores as biomarkers for neurological disorders. The Rademakers lab leads cutting-edge research into risk genes and molecular mechanisms in Frontotemporal Dementia (FTD), while
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into risk genes and molecular mechanisms in Frontotemporal Dementia (FTD), while the Sleegers lab specializes in Alzheimer’s Disease (AD), both leveraging next-generation sequencing and innovative
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-hydrated alkali-silicate melts that enable efficient zeolite formation under mild conditions. Molecular modeling and experimental characterization show that the type and concentration of the alkali cation
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with your supervisory team. This project will involve experimental design and require strong programming and analytical skills. Collaborate in a team: Work closely with other research project members
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; (ii) to deeply characterize their properties in vitro (affinity, specificity, inhibition constant and mechanism of inhibition, stability, binding epitopes, structure of the VHH-MMP9 complex),(iii
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significantly affects healthy brain tissue, particularly in children, since developing brains are susceptible to radiotherapy-induced neurotoxicity. The mechanisms driving cognitive decline need to be addressed
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strategies, with a focus on singlet oxygen production and suppression in photoelectrochemistry and sensing applications. By evaluating different quenching mechanisms (e.g., proximity-based singlet oxygen
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the motor design can be modified to make the windings in the machine more robust against thermal variations or mechanical vibrations. The work includes a significant experimental part, i.e. making prototypes