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pathway. Additionally, finite element theoretical modelling and density functional theory calculations will be used to further increase our understanding of the photo-reduction mechanism. Correlating
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from human genetics, genomics, protein biochemistry and neuronal and glial cell biology to integrative systems and computational biology. Models include yeast, fly, mouse, and pluripotent human cell
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include 1) a murine (diet-induced obesity) model, 2) acute and chronic exercise paradigms, 3) treatment with peripherally restricted enzyme-based eCB modulators, 4) multi-tissue molecular analyses and 5
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-causing mutations. Finally, we will validate the identified key (epi)genetic molecular and eplore their therapeutic potential in in vitro and in vivo disease models. Profile The candidate should: have an
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, will serve as input to generate a statistical prediction model, that will be built together with the bioinformatics team. You will publish scientific articles related to the research project, disseminate