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in the preparation, organization, and evaluation of replication deficient viral vectors Maintaining a transgenic mouse colony, including breeding, weaning, and genotyping Conducting survival procedures
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lentiviral and AAV viral vectors Desirable Application and Interview Demonstrable experience in assays of neuronal or synaptic function (electrophysiology, imaging (e.g., pHluorin)-based assays) Desirable
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website: https://glykys.lab.uiowa.edu Position Responsibilities Record, plot, analyze and interpret data independently using electrophysiological and imaging techniques, including two-photon and whole-brain
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neuronal cultures, neurons derived from induced pluripotent stem cells (iPSCs), and animal models using viral vectors — to test molecules currently under development. The work plan will involve a combination
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-scale multi-area in vivo neural recording, wireless electrophysiology in freely moving animals, custom-engineered sensory-motor behaviors, neural perturbation, viral labeling, and computation. Our work is
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Requirements PhD and/or MD degree in neuroscience, biological sciences or a related field. Experience with mouse genetics/behaviors, electrophysiology, viral vectors, stereotaxic surgery and molecular/cellular
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and use of viral vectors; site-directed mutagenesis; fluorescence and confocal microscopy; morphological analysis of developing neurons; neuronal migration analysis; electrophysiology (patch-clamp
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, Clin Infect Dis 58: 1424–1429. https://doi.org/10.1093/cid/ciu102 Chalghaf B, Chemkhi J, Mayala B et al. (2018). Ecological niche modeling predicting the potential distribution of Leishmania vectors in
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 10 hours ago
approaches, we seek to develop novel viral vector technology to create novel therapeutic strategies to treat neuronal dysfunction and degeneration to improve the quality of life of individuals who suffer from