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focuses on methodological development in cryo-electron microscopy (cryo-EM), particularly in image reconstruction and 3D volumetric analysis of macromolecular structures. Rather than aiming to incrementally
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-generation imaging technologies to map the molecular and structural architecture of the brain with nanoscale precision. We integrate Expansion Microscopy (ExM) with neurobiology to uncover mechanisms
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. • Perform simple techniques in cell biology and microscopy: examples include cell isolation and culture procedures, immunocytochemistry, tissue cryosectioning, microscope imaging, cell sorting, and some basic
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-operando Raman experiments on glass corrosion Developing and constructing fluid cells with integrated alpha radiation sources Performing post-mortem analyses (electron microscopy, e.g. EPMA, SEM, and X-ray
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educational technologies, such as virtual histology tools (digital microscopy, virtual slides, augmented/virtual reality technologies, 3D histological experiences) and online resources to provide engaging
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The advertised doctoral position will be carried out at the University of Pisa (https://www.unipi.it/ ; https://www.biologia.unipi.it/) with the most of the research work carried out at the International Centre
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histological techniques and immunocytochemistry confocal microscopy transmission electron microscopy image analysis using dedicated software (eg Neurolucida for confocal, Neurolucida Explorer, Meta Morph and
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devices using broadband spectroscopy and electron microscopy The position offers a stimulating interdisciplinary environment and opportunities to develop advanced skills in numerical optimization
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. Jennifer McManus, examining protein phase transitions associated with biomolecular condensation in-vitro using a range of scattering and fluorescence microscopy techniques. The overall aim is to understand
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of synaptic protein complexes at near-atomic resolution by cutting-edge technologies cryo-electron microscopy and tomography (cryoEM/ET), and other biochemical and biophysical approaches. This role of person