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. This position will focus on: (1) sustaining the long-term evolution experiment with E. coli; (2) employing and refining existing methods to measure phenotypic and genomic changes in this and other similar
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activates its specific target in Pseudomonas aeruginosa, we will design, develop and test novel anti-biofilm compounds with broader activity against the WHO priority pathogens Escherichia coli, Klebsiella
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recombinant proteins from E. coli , yeast, cell cultures, and/or plants Perform protein–protein interaction assays such as Co-immunoprecipitation (Co-IP), yeast two-hybrid (Y2H), Biolayer Interferometry (BLI
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. You will use this approach to determine how existing inhibitors affect E. coli DNA polymerase I, then apply it to Staphylococcus aureus (MRSA) polymerase polC to explore how experimental antibiotics
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for the production of well characterised tau samples for use in mechanistic studies across the UK DRI. This will include: Expression, purification and quality control of recombinant tau from E. coli and mammalian
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and the Bio-Nano Sensing group on the expression, modification and testing of new protein-based sensing systems. The successful candidate will lead on the design, recombinant expression (E. coli ) and
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limited to salmonella, Listeria, E. coli, Campylobacter, hot acids, bases, ethers and other chemicals. Special Requirements – Please contact your recruiter with questions regarding which activities apply by
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quality control of viral vectors using methods such as qPCR Experience in cloning, protein expression in E. coli, and purification Experience in analytical methods including SDS Page, Western blot, ELISA In
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infectious diseases are present. Specific hazards of the position are, but are not limited to salmonella, Listeria, E. coli, Campylobacter, hot acids, bases, ethers and other chemicals. Special Requirements
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to prevent and/or mitigate the impact of E. coli and Klebsiella spp. infections, including those associated with antimicrobial resistance (AMR). As part of this post there is an opportunity to analyse large