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matter, such as how droplets form, merge, and stay apart. This research not only deepens our understanding of chemistry but also supports the development of new materials, medicines, and environmentally
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HBIGS Heidelberg Biosciences International Graduate School | Heidelberg, Baden W rttemberg | Germany | about 2 months ago
segments—is a key pathological feature contributing to fibrosis and renal decline. Lipid droplet (LD) formation occurs in the endoplasmic reticulum (ER) once sufficient triacylglcyerol (TAG) has built up in
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, N. and Michelin, S., 2021. “Instability and self-propulsion of active droplets along a wall.” Phys. Rev. Fluids, 6(11), p.114103. Desai, N. and Michelin, S., 2022. “Steady state propulsion
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chemistry. Candidate enzymes are mechanistically investigated, structurally characterised and subsequently improved by directed evolution. Ultrahigh-throughput screening in microfluidic picoliter droplets
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this project, we will move towards phase-separating droplets with more than one component as they typically occur in physiological conditions. We will use a variety of techniques, including small-angle X-ray
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droplets; use super-resolution microscopy to investigate the molecular arrangement on the surface of milk fat globules and plant lipid droplets; develop chemical analytical tools (NMR, HPLC) to track
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-chemical mapping to unravel the structure-function properties of single milk fat globules and plant lipid droplets; use super-resolution microscopy to investigate the molecular arrangement on the surface
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the Job related to staff position within a Research Infrastructure? No Offer Description PhD Project Role of glycosphingolipids in lipid droplet formation during diabetic kidney disease (Simons420
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on host and dietary glycosides thanks to a large panel of carbohydrate active enzymes (CAZymes). In this project, the human gut microbiome will be screened using droplet-microfluidics for functions of human
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single filaments and single droplets to composite networks using techniques such as optical tweezers, fluorescence microscopy and atomic force microscopy. The concrete activities during the project will