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dynamic group investigating mitochondrial genetics and function using Drosophila as the model (http://themalab.co.uk ). The candidate will use genetic and biochemical approaches to study mitochondrial DNA
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including single-cell genomics by next-generation sequencing, in situ single-cell analyses of DNA and RNA by Fluorescent in situ Hybridization (FISH), and CRISPR gene editing to induce genomic instability and
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mechanisms that promote healthy ageing and identify interventions and potential drug targets. Our research areas include: DNA Damage & Repair Genetics & Epigenetics Immunology & Inflammation Membrane & Lipid
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necessary. Techniques that will be used include DNA/RNA extraction, qPCR, Gel electrophoresis, cell culture, Fluorescence and Confocal microscopy and associated imaging analysis and Western blotting. Basic
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research activities. Solid theoretical and practical knowledge in molecular biotechnology techniques (such as gene cloning and recombinant protein production). Knowledge on DNA, RNA and protein extraction
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environmental stress in the field. In this role, you will perform alpha-amylase enzyme assays and falling number testing in the laboratory, prepare protein and DNA extractions from wheat tissue, and conduct
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cells to develop a quantitative model. Once established, predicted separation mechanisms need to be tested.You will perform these experiments. Your tasks will include: Adapt existing DNA labeling
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RNA/DNA isolation, RT-qPCR Immunofluorescence and confocal imaging Mentor trainees and contribute to institute-wide collaborations Contribute to manuscript preparation, grant applications, and
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pediatric leukemia. Our team’s unique strength lies in its expertise in chromatin biology and non‑coding DNA, uncovering how gene regulation shapes disease. You will join a supportive, curiosity‑driven
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enriches the large-scale patient cohorts characterized over the past decade. This approach has resulted in the discovery of how unrepaired DNA lesions persist after chemical insults, resulting in large-scale