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. Investigate signaling pathways associated with cancer driving mutants. Perform xenograft experiments. Generate and analyze human and microbial genomic sequencing data from tumor DNA and RNA. Plan, design and
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involving signaling between nociceptors and non-neuronal cells in models of bladder dysfunction, as well as work closely with mechanical, electrical, and biological engineers to develop tools to study and
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cell lines. Perform functional validation of CRISPR-generated driver mutants. Investigate signaling pathways associated with cancer driving mutants. Perform xenograft experiments. Generate and analyze
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technologies will be used to investigate G protein-coupled receptor (GPCR) signal transduction as it relates to cardiovascular disease, and in particular the molecular basis for ligand-mediated β2-adrenergic
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). Our lab is a highly-creative and and dynamic Drug Discovery lab involved in cutting-edge technologies collaborating internationally on projects with other labs. We specialize in GPCR signaling and
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versus host disease (GVHD), and cancer immunotherapy. Specific areas of interest include inflammatory cytokine networks that contribute to GVHD, inflammatory cytokine signaling and regulatory pathways
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pharmacology and using protein structure to design and screen compounds as potential drugs at various GPCR signaling pathways aimed at treating depression, pain, cancer, and various other diseases. This post
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), while the other is a fibroinflammatory adipocyte progenitors (FAPs). As their names implies APC are pre-adipocytes which given the proper signals, differentiate into mature adipocytes, while FAPs, can
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concepts; mathematics; written and computer documentation; data utilization, problem solving, critical thinking, and writing skills. Skills and abilities: Basic biochemistry techniques including but not
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sequencing, analysis of proteins and enzymes, histological analysis including immunohistochemical techniques. Technical expertise in computer data bases and statistical analyses. Demonstrated proficiency in