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involving signaling between nociceptors and non-neuronal cells in models of bladder dysfunction, as well as work closely with mechanical, electrical, and biological engineers to develop tools to study and
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. Investigate signaling pathways associated with cancer driving mutants. Perform xenograft experiments. Generate and analyze human and microbial genomic sequencing data from tumor DNA and RNA. Plan, design and
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cell lines. Perform functional validation of CRISPR-generated driver mutants. Investigate signaling pathways associated with cancer driving mutants. Perform xenograft experiments. Generate and analyze
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). Our lab is a highly-creative and and dynamic Drug Discovery lab involved in cutting-edge technologies collaborating internationally on projects with other labs. We specialize in GPCR signaling and
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pharmacology and using protein structure to design and screen compounds as potential drugs at various GPCR signaling pathways aimed at treating depression, pain, cancer, and various other diseases. This post
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versus host disease (GVHD), and cancer immunotherapy. Specific areas of interest include inflammatory cytokine networks that contribute to GVHD, inflammatory cytokine signaling and regulatory pathways
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), interpersonal, and organizational skills. Proficiency with computer aided design and computational modeling software packages (e.g.; SolidWorks, Ansys, Abaqus, Fluent, SimVascular, etc). Preferred Schedule: Full
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concepts; mathematics; written and computer documentation; data utilization, problem solving, critical thinking, and writing skills. Skills and abilities: Basic biochemistry techniques including but not
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sequencing, analysis of proteins and enzymes, histological analysis including immunohistochemical techniques. Technical expertise in computer data bases and statistical analyses. Demonstrated proficiency in
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diseases including coarctation of the aorta. This work will involve processing of medical image data, creation of idealized and subject-specific computational models, and/or implementation of a computational