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Description In the Division of Diagnostics and Differential Psychology, we investigate systematic patterns and processes of personality development and personality-context transactions, with a focus
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for implementing ONNs. Modeling, simulate and benchmark different computing tasks such as combinatorial optimisation tasks and solving partial/ordinary differential equations with ONNs. Design and tapeout ONN chips
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on the development of regulatory tools to improve CRISPR-Cas editing for neurological diseases. You will work with a wide range of methods, including molecular biology, culture and differentiation of human iPSCs
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stem/progenitor cell plasticity (HSPCs), and leukemic transformation. The project will use innovative 2D and 3D HSPC/MSC co-culture models, functional clonogenic and differentiation assays, bulk and
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genes. The doctoral candidate will acquire a broad set of skills, including trans-differentiation of fibroblasts into neurons (iNeurons), development and screening of antisense oligonucleotides (AONs
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, including trans-differentiation of fibroblasts into neurons (iNeurons), development and screening of antisense oligonucleotides (AONs), live-cell imaging, and transcriptomic analyses. Laboratory work will
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mathematics, physics, computer science, engineering, or a related quantitative field. Strong knowledge of differential equations and applied mathematical modeling. Proficiency in at least one scientific
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for implementing ONNs. Modeling, simulate and benchmark different computing tasks such as combinatorial optimisation tasks and solving partial/ordinary differential equations with ONNs. Design and tapeout ONN chips
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to promote pancreatic cancer progression. Our laboratory and others have demonstrated that CAFs are characterised by different populations that can differentially contribute to tumour growth, metastasis
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. However, upon aging, HSC become dysfunctional and show differentiation imbalances toward an increased production of myeloid cells at the expenses of the adaptive immune lymphocytes. This has been associated