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experiments Develop, optimize cellular assays and CRISPR engineering using human iPS stem cell models and differentiation systems (2D or organoids) Perform functional validation of candidate hits using
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. However, upon aging, HSC become dysfunctional and show differentiation imbalances toward an increased production of myeloid cells at the expenses of the adaptive immune lymphocytes. This has been associated
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considering the standards of GIANT-REGAIN by means of differential GNSS analysis and Precise Point Positioning, respectively determination of the bedrock displacement due to present-day ice-mass changes using
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