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funded by the French National Research Agency (ANR) and involves five partners: the BSC – UMR7242 laboratory, the IGBMC (UMR7104) and TBI (INSA Toulouse) for molecular modeling, as well as the LSMIS
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&matricule_prop=67533 Post-translational modifications (PTMs), such as phosphorylation, ubiquitination, glycosylation, and SUMOylation, are key regulators of protein function, shaping immune signaling and
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and tethering. Combining functional approaches, (live) imaging and quantitative smFISH, (s)he will particularly focus on the contribution of localized RNA binding proteins and of the actin cytoskeleton
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biology, largely due to ongoing discussions about the extent to which it operates in both sexes. Classic theory posits that typically males, but not females, compete for access to mates. Until today
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resources to carry out the PhD project. This PhD is part of an interdisciplinary research project, involving mathematicians, molecular biologists, parasitologists, and philosophers from France, the
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Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Thesis proposed as part of an ANR Industrial Chair with
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Research Infrastructure? No Offer Description The PhD will take place at LAMIH-UMR CNRS 8201, Université Polytechnique Hauts-de-France, Valenciennes, France. It is part of the JCJC ANR TeCAPE project
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of neural circuits essential for adaptation. The successful candidate will explore the dynamics of neural populations in key brain regions for decision-making and behavioral control: the frontal cortex and
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, engineering, bioinformatics, machine learning, artificial intelligence) to support minimally invasive and targeted preventive and predictive medicine capable of limiting age-related functional disorders
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formation machinery (Grey, Baudat, de Massy 2018). Interestingly, in organisms, where PRDM9 is absent, or in mutant mice for PRDM9, DSBs still form, but they localize at functional genomic elements (FE) such