30 density-functional-theory-molecular-dynamics PhD positions at University of Cambridge in Uk
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of these factors. The work will involve genomic, proteomic and molecular approaches to decipher how these proteins contribute to NEPC and to explore if they can be therapeutically blocked. We aim to understand how
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formation, dynamics and functions of four-stranded DNA G-quadruplex structures and modified DNA bases in the genome (e.g. see Genome Biology, 2025 25, 155; Nature Chemistry, 2025, 17, 875; PNAS, 2024, 12(7
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PhD studentship: Defining the role of the pioneer factor FOXA1 in hormone-dependent cancer Supervisor: Professor Jason Carroll Course start date: 1st October 2026 Project details For further
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Cambridge Institute (CRUK CI), to investigate the molecular mechanisms of small RNA-mediated chromatin silencing. As a whole, the Hannon laboratory has broad interests that range from discovery research
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dynamics and tissue morphogenesis during embryo development using cellular, molecular and mechanical approaches. Cell movements underlie tissue patterns and shapes. Using chick embryos as the model system
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understood. This project will combine molecular, cellular, and physiological approaches to explore how exercise reprograms metabolic and inflammatory pathways that connect cardiac function to systemic health
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screens. Nature Reviews Molecular and Cell Biology 2023. 24, 477-494. Awwad, S.W., Doyle, C., Coulthard, J., Bader, A.S., Gueorguieva, N., Lam, S., Gupta, V., Belotserkovskaya, R., Tran, T-A
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and molecular biology techniques (e.g. RNA/protein analyses). Experience in mouse work, organoids, CRISPR, flow cytometry and computational skills is highly desirable. Please note that working with
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. The project will be jointly supervised by Dr Susanne Bornelöv (Biochemistry; https://www.sblab.uk ) and Dr Lukas Westlake (AstraZeneca), and the successful applicant will have the opportunity to work across
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of Cambridge Department of Medicine Molecular Immunity Unit, housed within the MRC Laboratory of Molecular Biology. Shortlisted candidates will be invited to visit the institute to deliver a seminar and