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Development lab to create a better understanding of the role of DNA methylation in gene regulation in healthy and disease. The candidate will explore different types of (epi)genetic data, with a main focus on
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, evolutionary theory, quantitative genetics, data science, toxicology, and law. Within this project, our group at the CRG focuses on the analysis of bulk and single cell RNA-seq from five different model species
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, in particular). Our lab is generating large-scale, state-of-the-art gut metagenomics data for thousands of genetically heterogeneous laboratory rats whose gut metabolome and behaviour have previously
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, and to develop therapeutic avenues. The group is particularly interested in understanding how genomic information is used to direct cell-specific gene expression, and to pinpoint gene regulatory defects