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-energizing exhausted T cells, it is becoming apparent that many checkpoint drugs act on specific subsets of ‘stem like’ T cells, which are present in the lymph nodes, or other sites such as the tumour itself
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biology, molecular biophysics, structural biology and particularly genomics. Students will contribute to one or more of our primary research areas below: Our main area of interest is on the structure and
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., Balasubramanian, S., Jackson, S.P. KLF5 loss sensitizes cells to ATR inhibition and is synthetic lethal with ARID1A deficiency. Nature Communications 2025. 16(1):480. Yard, B.D., et al., Cellular and Genetic
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