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of Ect2 in PDAC patient tumours The project will use a combination of cell and molecular biology approaches (including CRISPR gene editing, western blotting, flow cytometry), advanced microscopy (live cell
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. -Proven experience in genome editing techniques (e.g., CRISPR/Cas systems, prime editing, knock-in strategies). -Strong skills in molecular cloning, PCR-based genotyping, and construct design. -Experience
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emphasis on single-cell RNA sequencing, bulk and single-cell ribosome profiling, proteomics, CRISPR screening data (single-cell CRISPR approaches) and molecular recording data. The Institute for Regenerative
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. CRISPR/Cas or related techniques - highly desirable) A strong interest in cellular agriculture/cultivated meat is essential, although specific prior experience in this area is not expected or required
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engineering (e.g. CRISPR/Cas or related techniques - essential) Prior experience with epigenetic editing or methods will be advantageous (but is not required for an applicant to be considered) Experience in
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cardioids, CRISPR gene editing, high-throughput CRISPRko/i/a screening, single-cell multiomics, tissue engineering, and animal models. We welcome candidates with expertise in iPSC biology, functional genomics
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heterogeneity of their environments. For more details, please view www.bussilab.com and https://idmxs.org/research-theme-2/ We are looking for a highly motivated and creative Postdoc Research Fellow to join our
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a supportive and hardworking team of scientists based in the School of Biosciences and the Bateson Centre. The student will use cutting-edge techniques such as CRISPR/Cas9 gene editing, light sheet
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for targeted therapeutics, genes that could act as an “Achilles heel” for cancer cells while minimizing off-target effects on healthy tissues. To approach this, we use targeted and large-scale CRISPR/Cas9-based
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progression and therapy resistance. This position will leverage cutting-edge approaches including spatial transcriptomics, CRISPR-based functional genomic screening, and patient-derived xenograft (PDX) models