Sort by
Refine Your Search
-
Listed
-
Category
-
Country
-
Program
-
Field
-
research laboratory uses stem cells for the study and treatment of diabetes. We have a wide diversity of projects involving stem cells differentiation, genetic engineering with CRISPR, disease modeling
-
; performs a variety of molecular, cellular, and biological research techniques and procedures including maintenance and differentiation of human iPSC lines, CRISPR-based genome editing, cloning, qPCR, gel
-
, University of Pennsylvania. Our lab specializes in therapeutic gene editing, with a specific focus on using next-generation CRISPR tools for in vivo gene editing to address cardiovascular, metabolic, and other
-
mammalian cell lines, fluorescence microscopy (including live-cell imaging), and genome editing approaches (e.g. CRISPR-based tagging) is advantageous but not required. The role requires flexibility
-
liquid handling robots. Experience in bioimage analysis, for example using CellProfiler, R Bioconductor, ImageJ, and ML models. Experience in genetic (CRISPR) screening. Ability work efficiently and
-
. The iPSC lines we use are derived from patients or isogenic lines in which we induced disease-associated variants using CRISPR-Cas9. The iPSC-based models we have in the lab range from 2D cultures containing
-
training. Experience must be demonstrated in zebrafish handling, maintenance, and genetic editing (CRISPR/Cas9), flow cytometry, cell sorting, and in vivo imaging, as well as in molecular cloning, qPCR, and
-
novel regulators of the B cell survival, proliferation and crosstalk with other immune cells. The PhD student will further investigate this using techniques such as genome editing (CRISPR), RNA sequencing
-
primary samples from patients. We will identify functions of ncRNAs using CRISPR interference, RNA pulldown experiments, RNA profiling, mouse models, and molecular biology techniques. This will help better
-
the PhD student using technics such as genome editing (CRISPR), RNA sequencing, use of primary samples, functional studies with various in vitro and in vivo mouse models. The research is also relevant