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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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liquid handling robots. Experience in bioimage analysis, for example using CellProfiler, R Bioconductor, ImageJ, and ML models. Experience in genetic (CRISPR) screening. Ability work efficiently and
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single-cell analyses of DNA and RNA by Fluorescent in situ Hybridization (FISH), and CRISPR gene editing to induce genomic instability and study its consequences on tumor transformation and therapy
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the Guilliams and the Saelens team. Research Project In this research project you will apply in vivo CRISPR screens to study the molecular mechanisms driving liver regeneration. This project is supported by
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machinery and permit functional characterisation. Cell cycle inhibitors may be employed to investigate cell cycle checkpoints, and molecular approaches (e.g. fluorescent tagging, RNAi, CRISPR/Cas9 etc) will
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characterize novel photoreceptors in marine Synechococcus using CRISPR and protein biochemistry approaches. This project is funded by the NSF Systems and Synthetic Biology Program and builds on our successful
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-specific promoters and the human TET1 DNA demethylase, as well as CRISPR-based vectors that target ROS1/TET1 activity to specific genomic regions. TRAINING AND SKILLS This project offers comprehensive
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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assays is highly desirable. Expertise in CRISPR-Cas9 genome editing (knockout and correction) and in NGS workflows—such as ChIP-seq, RNA-seq, miRNA-seq, single-cell RNA-seq preparation, and CUT&RUN—is
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situ hybridization. Help with lab jobs, as needed. Make CRISPR mutants. Maintain lab notebook. Other duties and responsibilities as assigned Qualifications Bachelor of Science and 0 to 1 year of