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-ISCIII (PI24/00173)", with the destination being the Foundation for Health Training and Research of the Region of Murcia. Where to apply Website https://rrhh.ffis.es/rrhh/ofertaEmpleo.jsf?id=1944
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induced pluripotent stem cells (iPSCs), including reprogramming, maintenance, and differentiation into cardiomyocytes and non-myocyte cells; utilizes CRISPR-Cas9 genome editing to model genetic
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microscopy, CRISPR, omics approaches (Chip-seq, proteomics), or bioinformatics. How to apply: Cover letter: your motivation to apply for this position and description of your research interests. CV: Highlight
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. We employ a cutting-edge toolbox including 3D tumor organoid cultures, single-cell transcriptomics and CRISPR-based genome engineering that allow us to investigate tumor heterogeneity and cellular
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knockouts or knockdowns in patient-derived iPSCs (via CRISPR-Cas9 or siRNA), after which the iPSCs would be differentiated into neutrophils. The phenotypic effect of these interventions would then be verified
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will have expertise in molecular and cellular biology and will notably perform labelling and imaging by STED of primary culture, modification of the cells by CRISPR-Cas9 to introduce mutations, and
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Carl von Ossietzky Universität Oldenburg | Oldenburg Oldenburg, Niedersachsen | Germany | 5 days ago
recombination, marker/deficiency selection, etc.) Generation of novel transgenic Drosophila lines through appropriately designed and applied mutagenesis strategies (e.g. CRISPR-Cas/UAS/Gal4/LexA, etc.) Design
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engineering are highly qualifying merits. Know-how of genome editing using CRISPR/Cas9, microbial cultivation/fermentation, bioinformatics and analytical techniques are highly meritorious. Contract terms
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cytometry, immunohistochemical, iPSC culturing, gene induction and knockdown with CRISPR and viral vectors and statistics. Prior experience with preclinical models of neurodegeneration is preferred
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viral vectors, CRISPR-based tools and pharmacological approaches. -Perform bioinformatic analysis and integration of transcriptomic, epigenomic and epitranscriptomic datasets. -Prepare scientific reports