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CeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences | Austria | about 2 months ago
Nature), for high-content CRISPR screening (Bock 2022 Nature Reviews), and CAR T cell engineering (Datlinger 2025 Nature); Condensates, Chromatin and Translational Control in Pediatric Cancer (Grebien Lab
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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Robson (c.n.robson@ncl.ac.uk ) Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/ Find out more about our Research Institutes here: https://www.ncl.ac.uk
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opportunity to pursue an independent programme of research in this critical area and to join Oxford University’s Tuberculosis Grand Challenge (https://www.ineosoxford.ox.ac.uk/ioi-grand-challenge-tuberculosis
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. 2022;6(1):88-102. doi:10.1038/s41559-021-01586-x Developing CRISPR tools for targeting tumour suppressors in Mesothelioma Primary supervisor: Daniel Murphy Project summary oin the world-leading
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engineering (CRISPR/Cas), qPCR, and work with reporter lines carry out phenotyping, imaging, and hormone-related assays/tracing contribute to transcriptomic/proteomic experiments and integrative analysis
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confocal to super-resolution imaging, imaging of living cells and small animals. Other facilities include single-cell technologies, small molecule and CRISPR screening, high-throughput sequencing
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in early mammalian development. Involve whole genome amplification, NGS, bioinformatics, immunostaining and microscopy, induction of site specific DSBs using Crispr/Cas9 and the evaluation of genetic
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Natural Killer cell biology assays, both in vitro and in vivo in xenogeneic models (70% of effort) CRISPR editing of tumor cell lines and primary NK cells will be necessary to assess for the project