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of these genes to the osteoarthritis phenotype. Analyses include CRISPR/Cas9 genome editing in mouse, scRNA-seq, spatial profiling, WES/WGS, and tissue culture. The candidate should be prepared to analyze gene
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of these genes to the osteoarthritis phenotype. Analyses include CRISPR/Cas9 genome editing in mouse, scRNA-seq, spatial profiling, WES/WGS, and tissue culture. The candidate should be prepared to analyze gene
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experiments. Lentiviral transduction techniques for ORF-overexpression experiments or RNAi and CRISPR-Cas9 knockdown/knockout experiments. Performing detailed characterization and cellular mechanism of action
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 1 day ago
. Experience with genome editing technologies such as CRISPR is a plus. * For dry-lab applicants: Ph.D.-level training and research experience in analyzing multi-omics next-generation sequencing data is required
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University of California, San Francisco | San Francisco, California | United States | about 1 month ago
and Engineering to Accelerate Discovery (READY) Center Team. This role will focus on utilizing cutting-edge CRISPR gene editing methods to support cell engineering projects that are part of a larger
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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the delivery of payloads including mRNA, siRNA, pDNA, and CRISPR-Cas ribonucleoproteins (RNPs), and/or small molecular drugs, for therapeutic applications. Our primary research thrusts are centered on tackling
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candidate will translate new insights into identifying new drug targets for improved patient outcomes in periodontal health. Dr. McCulloch’s laboratory is described here: https://discover.research.utoronto.ca
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genome editing. Your job This project aims to systematically identify and characterize regulators of early transcription termination. Potential approaches will involve pooled CRISPR screens, genome editing
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, and maintain mouse embryonic stem (mES) cells and human induced pluripotent stem (hiPS) cells, employing advanced genetic modification techniques including CRISPR/Cas9 genome editing. • Perform directed