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. The specific goal of this work is to unravel the molecular mechanisms of blood cell development using state-of-the-art technologies such as CRISPR screens, proteomics, and multi-omics approaches. About you: You
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biology experience. During this position, the post-holder will undertake a range of molecular and cell biological activities, including use of CRISPR-Cas9, primary cell culture, and western blotting
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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/bayesian/deep-learning analyses, with functional validation in spruce via CRISPR-Cas9 and nanoparticle delivery. The postdoc will join Professor Nathaniel R. Street’s team at UPSC, working closely with
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scientific fields and a multitude of educations ranked highly in international comparison. Recent breakthroughs at Umeå University include deciphering the molecular mechanisms of the bacterial CRISPR-Cas9
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for setting up experimental systems to study type VI CRISPR-Cas defense mechanisms and analyzing collateral RNA damage using RNA-sequencing. KEY DUTIES: 60 % 1. Conduct research on RNA-targeting type VI CRISPR
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molecular cell biology (using techniques such as cell culture, CRISPR/Cas9 based genome editing, protein expression and interaction analysis, confocal and live cell microscopy), as well as bioinformatics
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, confocal microscopy) and molecular level (RNA-seq, spatial technologies) B2. Knowledge of gene manipulation techniques such as CRISPR and metabolic experimental techniques such as Seahorse, SCENITH
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Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt | Germany | 2 months ago
cultures (including patient-based material), work with lung organoids and organoid-immune cell co-culture systems, perform CRISPR/Cas9 gene editing, and investigate epithelial homeostasis & stress responses
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cell culture, CRISPR/Cas9 based genome editing, protein expression and interaction analysis, light microscopy and cancer assays. A solid background in data analysis, bioinformatics and presentation