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-leukemia (e.g. Beneyto-Calabuig et al., Cell Stem Cell 2023 ). A specific focus is the use of genetic screens (E.g. CRISPR screens, Perturb-Seq, MPRA) in primary hematopoietic stem cell models
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: 1 year Appointment Start Date: Flexible Group or Departmental Website: http://www.sheltzerlab.org (link is external) How to Submit Application Materials: Email your application to Dr. Sheltzer Does
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Stanford Cancer Center Pediatrics Postdoc Appointment Term: Two years Appointment Start Date: 1/1/2026 Group or Departmental Website: http://www.sheltzerlab.org (link is external) How to Submit Application
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editing strategies (CRISPR/Cas and other emerging tools) in bacteria, fungi, and yeasts. Conduct metabolic engineering approaches to enhance the production of high value‑added compounds. Develop and
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will have the opportunity to work with: High‑throughput functional genomics: pooled CRISPR and base‑editing screens, barcoded overexpression libraries, massively parallel reporter assays. Advanced cell
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studying genome plasticity and drug resistance in fungal pathogens. We use comprehensive genomic techniques, including Illumina and MinION whole genome sequencing, qPCR, and CRISPR engineering. This
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with primary synovial cells obtained from joints from arthritis patients (e.g., CRISPR knock-outs and phosphoproteomics signaling), in vivo arthritis models in newly generated transgenic mice (e.g
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proteins identified from this screen will be validated using siRNA-mediated knockdown and CRISPR knockout in bacterial adherence assays to determine which specific cell surface proteins mediate interactions
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(https://www.unibas.ch/en/Research/Values-Ethics/Diversity-and-Inclusion.html ), we are committed to sustain and promote an inclusive culture, ensure equal opportunities and value diversity and respect in
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of the targets will avail of in vitro CRISPR/Cas9 screens and mechanistic studies to uncover novel potential vulnerabilities. Where to apply Website https://www.univr.it Requirements Additional Information