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to formulate and test hypotheses about how epigenetic factors control the life cycle of parasitic nematode, use transgenic and CRISPR methods to manipulate epigenetic regulators, and test the effects
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-2025). Scaling explains how the machinery that controls pattern formation in development adapts, so that organs of different sizes show proportioned structures: the same developmental machinery can build
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on understanding the role of the endosomal system in neurodegenerative disease. The endosomal system comprises an inter-connected series of intracellular membrane-bound compartments controlling protein and lipid
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