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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | about 1 month ago
to design novel anticancer treatments. In our studies we use human and mouse cancer cell lines and syngeneic as well as xenograft tumour models in mice. We also use 3D cell cultures, co-culture techniques
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poorly understood. To investigate this topic, we will use whole-genome re-sequencing and integrative approaches which combine population genomics with advanced spatial modelling techniques based
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animal models. As the ‘glycan shield’ in Lassa/Hendra/Nipah plays a major role in immune evasion, we explore the immunological effects of an interference with protein glycosylation leading to novel
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the Malopolska Centre of Biotechnology, Krakow, Poland. Scope of duties according to the Work Regulations of the Jagiellonian University Annex 1 to the Work Regulations of the Jagiellonian University – Model scope
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on an animal model, using a high-field MR tomograph 9.4 T, within the scope of the research project NCN OPUS: " New generation theranostic nanocarriers for detection, diagnosis and neuroprotective treatment
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to confirm the safety of the (nano)hormonechemotherapeutics. A key phase will be the development of a translational organoid model derived from patient tumor tissues that reflects the realistic tumor
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process of 3D-printed constructs. The selected models will undergo long-term culture and functional tests, such as cultivation in a perfusion system and mechanical testing, to evaluate the usability
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mountain river channels. In the initial phase of the project, their primary responsibility will be to generate orthophotos and digital elevation models (DEMs) of the study sites using drone imagery. Once
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of multinuclear low-valent iron and vanadium complexes supported by tailored N,N-donor ligands. These model systems will allow us to probe the intimate steps of N2 activation, explore cooperative effects between
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, obtained not earlier than 7 years before the year of employment in the project (not including maternity leaves), Strong MATLAB and/or Python programing skills – signal analysis, statistics, neuronal modeling