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The UKRI-funded 5-year project, 'Colombo: Layered Histories in the Global South City', selected for funding by the European Research Council under its 'HORIZON' programme, is recruiting to its
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for matching novel protein targets with their optimal expression conditions. Altogether, this project will provide new insights into the mechanisms limiting expression of challenging proteins and how
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, Su J, Eldridge MD, Riedel A, Serrao E, Rodewald HR, Mack M, Shields J, Cohen ES, McKenzie ANJ, Goodwin RJA, Brindle K, Marioni JC, Halim TY. (2020) ILC2-driven innate immune checkpoint mechanism
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target, since all known treatment resistance mechanisms are downstream of, and dependent on FOXA1. However, FOXA1 has been a difficult protein to study for technical reasons. We have developed a novel tool
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treatments that target AR have forced cancer cells to evade treatment and a newly characterised, but frequent escape mechanism is for cancer cells to lose dependence on AR and to take on features of a
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and an Industrial supervisor at Jaguar Land Rover (JLR). It falls within the remit of the Cambridge Engineering Design Centre (EDC), but interactions with other groups are expected, across and beyond
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technologies, bulk and single-cell RNA-sequencing, flow cytometry, multiplex immunofluorescence, and standard molecular biology and biochemistry techniques. A computational component may also be available