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will be tasked with the development of new models for the early detection of CIN cancers, applying bleeding edge computational methods and machine learning approaches to improve detection and
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The Centre for Doctoral Training in Nanoscience and Nanotechnology (NanoDTC) at the University of Cambridge invites applications for its 3.5-year interdisciplinary PhD programme. The programme
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tumours and metastases with the goal to design combinatorial therapeutic approaches. The project will involve the use of genetically complex organoid-derived transplantation mouse models of pancreatic
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on cell viability and DDR activation in established human cell models. The student will perform CRISPR screens to determine factors that affect resistance/sensitivity and follow these up with mechanistic
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chromatin profiling methods along with CRISPR/Cas9-meduated cell line engineering and various animal models. You will study the effects of the activation or depletion of chromatin-modifying enzymes using