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various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly
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project:*The Role of m6A Methylation in Response to Genotoxic Stress and in CancerSupervisor: Guillaume VarèsIn response to ionizing radiation (IR) exposure, cells trigger a variety of complex and
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.; Samal, J.; Pandit, A.; Négroni, L.; Soriano, N.; Monnier, A.; Mosser, J.; Chatziioannou, A.; Quillien, V.; Chevet, E.; Avril, T. IRE1 Endoribonuclease Signaling Promotes Myeloid Cell Infiltration in
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of brain and other mouse tissues.•Animal experimentation, including injections, perfusion, etc.•Molecular and cellular biology experimentation (e.g., PCR, Immunoblotting, cell culture)•Maintenance
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or the glutamate receptors, little is known about the interactome of neuronal nAChRs. We are looking for a highly motivated post-doctoral fellow to conduct an integrative structural biology approach to identify and
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methods for single-cell data analysis (tools developed by the team : https://github.com/cantinilab ). Single-cell high-throughput sequencing, extracting huge amounts molecular data from a cell, is creating
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statistically significant results on ferroelectric capacitor performance. The post-doctoral research will give a better understanding of the influence of dopants on local chemistry, electronic structure, phase
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. In cancer cells, DNA often accumulates in cytoplasmic micronuclei due to chromosome segregation defects, and senescent cancer cells amass cytoplasmic chromatin fragments (CCFs). We propose that AIM2
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. Our lab investigates the molecular and functional basis of virus-specific B-cell immune responses, with a particular focus on the role of antibodies in controlling human viral infections. Projects