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, The Netherlands) in the lab of Dorota Durek to test an engineered protease inhibitor in an in vitro model of skin scarring. More information on the scientific project is available here: Titre: Elucidation
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of isolated clones using biochemical, biophysical and imaging methods. Engineering of protein tools using chemical or genetic methods for use in a cellular environment. Validation of tools in cellular models
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chemistry, materials science or equivalent having carried out research in an experimental field related to the thesis. Core competencies: crystal growth thermodynamic modeling chemical and physical
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model that explains lattice distortions and branching mechanisms. (4) Analyze experimental data using advanced computational tools and present results in research meetings and scientific publications
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interpersonal skills and be rigorous and organised in his/her work. Experience in molecular/cellular biology and murine models is required. Experience in omic approaches,single cell RNA-seq technologies and
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experimental development, physicochemistry, and multiscale modeling for the implementation of innovative extraction technologies aimed at processing complex, polymetallic, and unconventional resources while
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), Biochemistry (production and purification of protein complexes), Structural biology (cryo-electron microscopy and image analysis). The final goal is to build a mechanistic model of substrate recruitment by
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tools • Modeling of devices with the finite element method • Micro-nano fabrication in the IEMN's clean room • Physical / Electrical characterization of devices • Participation in the ANTARES project
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emerging models by collaboratively exploring various computation models leveraging physical devices properties. This PhD work will focus on FPGA devices in order to build an accelerated spiking neural
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metabolism in type I interferonopathies within tissues. Using mouse models of these diseases, we will analyze how metabolic alterations contribute to inflammation and tissue damage. We will generate lipidomic