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genetic mutations. We aim to advance our understanding of these diseases and to develop and translate therapeutic strategies for future clinical practice. The applicant is expected to work on mouse models
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biochemistry, genomics, molecular genetics, cell biology, and model organism systems to uncover the mechanisms by which histone mutations disrupt human development and lead to disease. Our ultimate goal is to
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(including Crohn’s disease and ulcerative colitis) using molecular and cell biology, multi-omics technologies, murine models, and human tissues. We currently have three major focuses: 1) Innate lymphoid cells
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Position Summary The Ornitz Lab at WashU Medicine is seeking a highly motivated postdoctoral researcher with experience working with mouse models of development and disease. Candidates will have the
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. Computational and bioinformatic skills. Experience in microscopy. Generation and analysis of mouse models. Handling of human samples. Molecular biology skills including CRISPR, cloning and qPCR. In vitro cell
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guidelines based on risk modeling outcomes. This position is for an initial full-time, 12-month appointment, with the possibility for renewal for additional year(s), and the anticipated start date is October 1
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, single-cell multiomics, tissue engineering, and animal models. Our current research primarily focuses on four key areas: 1) Developing robust, chemically defined differentiation protocols to generate
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, to define novel biomarkers, and to identify novel therapeutical targets. We have pioneered in the integration of genetics with omic data to identify proteomic signatures and develop novel predictive models
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their degree in the near future) in Cancer Biology or a related field. Proficiency in experimental techniques such as cell/organoid culture, library construction, imaging and handling animal models. Experience
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multidisciplinary approach, spanning basic biology and translational medicine using mouse models and patient samples, tackles complex questions with profound implications for human health. Projects are available